I've actually done some research about a number of the different aftermarket tuners... Here's what I've been able to find out. Read on:
I actually have been paying fairly close attention to these debates on this and other forums. From the sounds of it, the concensus seems to be the Dobeck.
Personally, I have just ordered the Dobeck Gen. 4 for my 2011 Fatty. This decision came after using the Powercommander V and being left wanting something more. Why? Well, when it came to light that using that (without the self-tuner, and even then, to a degree) was basically "fooling" the ECM into different A/F mixtures, I didn't like that idea. From personal experience, my bike never seemed to run the same way twice. E.g. good one day, doggy the next, I was just dissatisfied.
My next idea was either the Dynojet Powervision or waiting for the Thundermax to come out for 2011 softails. What I liked about the Powervision was the ability to "reprogram" the ECM using real-time readings. I also liked the idea of the Thundermax where they just replace the ECM and program the T-Max using the equipment on the bike--and there is a TON of variables you can program in there. Everything from aftermarket exhaust to aftermarket cams is adjustable in the T-Max. Problem is, I'm EXTREMELY impatient--it's still not out! The problem with the Powervision? It's proprietary... You can only use it on ONE bike. You can use it on that one bike as many times as you like, but for $500+, I was having trouble seeing the value.
Enter the Dobeck. I have yet to hear a bad word about them. The Generation 4 provides real-time, analog gauged information about how rich/lean/mid-range your bike is running at any given time and the ability to make on-the-fly adjustments. THIS is the part that sold me! If I want to richen up the passing gear? Done! If I want to lean out the cruising speed? Done! With all this taken into account, the Dobeck is on its way!
With my impatient nature, rest assured it'll be installed the same day it's delivered! Unfortunately, I'll probably not be able to do anything in the way of performance reviews until the spring... Anyway, thought I'd share the stuff I learned from doing some research...