07 flhr, SE255 cam, 50,000 total miles on bike...I have a set of S&S standard lifters in it with bout 30,000 miles on them..they are adjusted bottomed out and backed off 2 or 3 flats cold...when I start the bike cold I get a little lifter rattle and around 1500 to 3000 rpm as I take off going through the gears it's a bit more louder.. after about 1 mile (as bike is a little warm) they are quiet...at any speed any rpm, wondering if thats a sign of wear and time to replace ???